전체메뉴
Article Search

VSI Vascular Specialist International

Open Access

pISSN 2288-7970
eISSN 2288-7989
QR Code QR Code

Original Article

상급 종합병원에 등록된 환자들에서 말초동맥질환 위험인자의 상대 위험도

Relative Risk of Peripheral Arterial Disease for Patients Registered in a Tertiary Referral Centre

이경희1ㆍ손민지2ㆍ최상태1ㆍ김정호3ㆍ변성수3ㆍ강진모1
Kyung Hee Lee, M.D.1, Min Ji Son2, Sang Tae Choi, M.D.1, Jung Ho Kim, M.D.3, Sung Su Byun, M.D.3 and Jin Mo Kang, M.D.1
Author Info +

Department of Surgery, Gachon University Gil Hospital1; Gachon University of Medicine2,Department of Radiology, Gachon University Gil Hospital3, Incheon, Korea

Department of Surgery, Gachon University Gil Hospital1; Gachon University of Medicine2,Department of Radiology, Gachon University Gil Hospital3, Incheon, Korea

Korean J Vasc Endovasc Surg 2012; 28(3): 119-125

Published August 30, 2012 https://doi.org/10.5758/kjves.2012.28.3.119

Copyright © The Korean Society for Vascular Surgery.

Article Tools

Share this article on :

Metrics

Article Tools
Article Tools

Abstract

Go to
Purpose: Peripheral arterial disease (PAD) is an increasing health problem, as we progress towards an aging society. The diseases known as risk factors of PAD are diabetes mellitus (DM), hypertension, and dyslipidemia, and PAD occurs consistently in patients with diabetes. The patients with PAD do not receive proper treatment at the proper moment, because PAD is almost asymptomatic, and most of the diagnosis is delayed. We aimed to determine the prevalence, risk factors and co-morbidities of PAD in patients who are managed for DM and hypertension in our referral center. Methods: Patients with diabetes and hypertension were selected from the Gachon University Gil Hospital. Data of the patients, including demographics and presence of risk factors, were collected using an interviewer-administered questionnaire. For PAD of the low limbs, the ankle-brachial index (ABI) was used, and the PAD of low limbs was defined as ＜0.9 ABI. For carotid artery stenosis (CAS), carotid duplex ultrasound was analyzed, and CAS was defined as ≥50% internal CAS. Results: Logistic regression analysis showed that old age (＞70) and diabetes were independent risk factors of PAD. As the risk factor number increased, the prevalence of PAD became higher. Conclusion: The prevalence of PAD is continuously increasing. Old age and diabetes were independently associated with a high risk of all-cause PAD patients. For timely and proper management of PAD, large-scale research is needed. Based on research, we should make a detailed plan about early screening, and treatment of PAD.

Keywords

Peripheral arterial disease, Risk factors, Mass screening

References

Go to
  1. Nguyen LL. Percutaneous treatment of peripheral vascular disease: the role of diabetes and inflammation. J Vasc Surg 2007;45 Suppl A:A149-A157.
  2. Criqui MH, Fronek A, Barrett-Connor E, Klauber MR, Gabriel S, Goodman D. The prevalence of peripheral arterial disease in a defined population. Circulation 1985;71:510-515.
    Pubmed CrossRef
  3. Hiatt WR, Hoag S, Hamman RF. Effect of diagnostic criteria on the prevalence of peripheral arterial disease. The San Luis Valley Diabetes Study. Circulation 1995;91:1472-1479.
    Pubmed CrossRef
  4. Selvin E, Erlinger TP. Prevalence of and risk factors for peripheral arterial disease in the United States: results from the National Health and Nutrition Examination Survey, 1999-2000. Circulation 2004;110:738-743.
    Pubmed CrossRef
  5. Norgren L, Hiatt WR, Dormandy JA, Nehler MR, Harris KA, Fowkes FG, et al. Inter-Society Consensus for the Management of Peripheral Arterial Disease (TASC II). J Vasc Surg 2007;45 Suppl S:S5-S67.
  6. Statistics Korea. 2007 Statistics for elderly population. Daejeon: Statistics Korea; 2007.
  7. Cho NH, Kim TH, Lee SS, Oh YH, Kim YH, Kim JS, et al. Understanding of the basic plan on low fertility and aging society in Korea: 2006-2010. Seoul: Korea Institute for Health and Social Affairs; 2006.
  8. Anderson CS, Linto J, Stewart-Wynne EG. A populationbased assessment of the impact and burden of caregiving for long-term stroke survivors. Stroke 1995;26:843-849.
    Pubmed CrossRef
  9. Yun WS, Rho YN, Park UJ, Lee KB, Kim DI, Kim YW. Prevalence of asymptomatic critical carotid artery stenosis in Korean patients with chronic atherosclerotic lower extremity ischemia: is a screening carotid duplex ultrasonography worthwhile? J Korean Med Sci 2010;25:1167-1170.
    Pubmed PMC CrossRef
  10. Management of peripheral arterial disease (PAD). TransAtlantic Inter-Society Consensus (TASC). Eur J Vasc Endovasc Surg 2000;19 Suppl A:Si-xxviii, S1-S250.
  11. McKenna M, Wolfson S, Kuller L. The ratio of ankle and arm arterial pressure as an independent predictor of mortality. Atherosclerosis 1991;87:119-128.
    CrossRef
  12. Li J, Luo Y, Xu Y, Yang J, Zheng L, Hasimu B, et al. Risk factors of peripheral arterial disease and relationship between low ankle - brachial index and mortality from all-cause and cardiovascular disease in Chinese patients with type 2 diabetes. Circ J 2007;71:377-381.
    Pubmed CrossRef
  13. Grant EG, Benson CB, Moneta GL, Alexandrov AV, Baker JD, Bluth EI, et al. Carotid artery stenosis: gray-scale and Doppler US diagnosis--Society of Radiologists in Ultrasound Consensus Conference. Radiology 2003;229:340-346.
    Pubmed CrossRef
  14. Jepson RG, Fowkes FG, Donnan PT, Housley E. Alcohol intake as a risk factor for peripheral arterial disease in the general population in the Edinburgh Artery Study. Eur J Epidemiol 1995;11:9-14.
    Pubmed CrossRef
  15. Vliegenthart R, Geleijnse JM, Hofman A, Meijer WT, van Rooij FJ, Grobbee DE, et al. Alcohol consumption and risk of peripheral arterial disease: the Rotterdam study. Am J Epidemiol 2002;155:332-338.
    Pubmed CrossRef
  16. Yi-mei D, Yu W, Yan L, Pei Y, Min-yan L, Liang L, et al. Prevalence and risk factors of peripheral arterial diseases in male Chinese octogenarians and nonagenarians with hypertension. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2011;33:162-168.
    Pubmed
  17. Fleming C, Whitlock EP, Beil TL, Lederle FA. Screening for abdominal aortic aneurysm: a best-evidence systematic review for the U.S. Preventive Services Task Force. Ann Intern Med 2005;142:203-211.
    Pubmed CrossRef
  18. Cosford PA, Leng GC. Screening for abdominal aortic aneurysm. Cochrane Database Syst Rev 2007;(2):CD002945.
    CrossRef
  19. Lekshmi Narayanan RM, Koh WP, Phang J, Subramaniam T. Peripheral arterial disease in community-based patients with diabetes in Singapore: results from a Primary Healthcare Study. Ann Acad Med Singapore 2010;39:525-527.
    Pubmed
  20. Weiner SD, Reis ED, Kerstein MD. Peripheral arterial disease:medical management in primary care practice. Geriatrics 2001;56:20-22, 25-26, 29-30.
    Pubmed
  21. Chung YS, Yoo HJ, Seo SO, Kim HK, Kim DM, Yoo JM, et al. Risk factors of peripheral vascular disease (PVD) and nutritional factors in diabetic patients over 60 years old complicated with PVD diagnosed by ankle-brachial index (ABI). J Korean Diabetes Assoc 1999;23:814-821.
  22. Nam SJ, Cho SR, Kim CS, Woo SG, Choi HJ, Kim SK, et al. Plasma concentrations of plasminogen activator inhibitor-1 (PAI-1) and lipoprotein(a) in non-insulin-dependent diabetes mellitus with peripheral vascular disease. J Korean Diabetes Assoc 1999;23:55-61.
  23. MacGregor AS, Price JF, Hau CM, Lee AJ, Carson MN, Fowkes FG. Role of systolic blood pressure and plasma triglycerides in diabetic peripheral arterial disease. The Edinburgh Artery Study. Diabetes Care 1999;22:453-458.
    Pubmed CrossRef
  24. Park JS, Kang JG, Hahm JS, Kang CM, Yoo WS, Park CK, et al. Risk factors for peripheral arterial disease among Korean diabetic patients. J Korean Soc Vasc Surg 2002;18:259-267.

Related articles in VSI

More Related Articles