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Table. 3.

Table. 3.

Demographic features and predictors for amputation in DFU

Risk factor DFU (n=73) Amputation (n=28, 38.4%) Univariate Multivariate


P-value P-value OR (95% CI)
Age (y) 0.044 0.274 0.487 (0.134–1.768)
 ≥60 37 (50.7) 10 (27.0)
Male 33 (45.2) 12 (36.4) 0.750 0.258 2.230 (0.555–8.965)
Site, right 36 (49.3) 10 (27.8) 0.067 0.083 3.063 (0.864–10.853)
Hypertension 47 (64.4) 15 (31.9) 0.128 0.531 0.644 (0.163–2.551)
DM control 0.542 0.165 2.997 (0.636–14.132)
 Insulin 23 (31.5) 10 (43.5)
Coronary artery disease 15 (20.5) 7 (46.7) 0.458 0.278 2.661 (0.454–15.607)
Cerebrovascular disease 16 (21.9) 7 (43.8) 0.616 0.230 2.360 (0.581–9.581)
Chronic kidney diseasea 10 (13.7) 3 (30.0) 0.732 0.336 0.384 (0.054–2.700)
COPD 19 (26.0) 8 (42.1) 0.696 0.789 1.212 (0.296–4.956)
HbA1c >9 19 (26.0) 7 (36.8) 0.875 0.785 0.816 (0.189–3.530)
Smoking 41 (56.2) 18 (43.9) 0.270 0.523 1.622 (0.368–7.150)
Dementia 7 (9.6) 1 (14.3) 0.239 0.391 0.280 (0.015–5.125)
Bed ridden state 6 (8.2) 3 (50.0) 0.669 0.599 0.500 (0.038–6.651)
Economic state 43 (58.9) 17 (39.5) 0.804 0.913 0.928 (0.243–3.550)
PAOD 24 (32.9) 9 (37.5) 0.916 0.682 1.354 (0.317–5.787)
Osteomyelitis 27 (37.0) 15 (55.6) 0.021 0.116 3.321 (0.743–14.838)
Leukocytosis 28 (38.4) 13 (46.4) 0.263 0.287 1.975 (0.565–6.909)

Values are presented as number (%).

DFU, diabetic foot ulcer; OR, odds ratio; CI, confidence interval; DM, diabetes mellitus; COPD, chronic obstructive pulmonary disease; PAOD, peripheral arterial occlusive disease.

Glomerular filtration rate <30.

Vasc Spec Int 2018;34:109-16 https://doi.org/10.5758/vsi.2018.34.4.109
© 2018 The Korean Society for Vascular Surgery