Vascular Specialist International : eISSN 2288-7989 / pISSN 2288-7970

Table. 2.

Table. 2.

Risk factors for major amputation in DFW with PAOD

Risk factor DFW with PAOD (n=76) Major amputation (n=29, 38.2%) Univariate Multivariate


P-value P-value OR (95% CI)
Age (y) 0.708 0.092 0.110 (0.008–1.435)
 ≥60 64 (84.2) 25 (39.1)
Male 38 (50.0) 12 (31.6) 0.238 0.080 6.096 (0.806–46.079)
Site, right 32 (42.1) 14 (43.8) 0.392 0.595 1.557 (0.304–7.966)
Wound infection 57 (75.0) 23 (40.4) 0.495 0.375 0.363 (0.039–3.410)
Hypertension 52 (68.4) 19 (36.5) 0.669 0.957 0.952 (0.154–5.885)
DM control 0.771 0.126 5.436 (0.623–47.428)
 Insulin 17 (22.4) 7 (41.2)
Coronary artery disease 26 (34.2) 13 (50.0) 0.125 0.074 5.502 (0.849–35.672)
Congestive heart failure 15 (19.7) 9 (60.0) 0.052 0.171 4.259 (0.534–33.962)
Cerebrovascular disease 20 (26.3) 10 (50.0) 0.204 0.398 2.402 (0.315–18.382)
Chronic kidney diseasea 20 (26.3) 10 (50.0) 0.204 0.467 0.500 (0.077–3.240)
COPD 24 (31.6) 9 (37.5) 0.936 0.589 1.681 (0.256–11.052)
Leukocytosis 42 (55.3) 22 (52.4) 0.005 0.019 8.457 (1.410–50.716)
HbA1c >9 18 (23.7) 7 (38.9) 0.942 0.855 1.231 (0.133–11.368)
Smoking 36 (47.4) 14 (38.9) 0.901 0.884 0.867 (0.127–5.902)
Dementia 20 (26.3) 10 (50.0) 0.204 0.167 3.859 (0.569–26.162)
Economic state 37 (48.7) 17 (45.9) 0.173 0.247 2.847 (0.484–16.749)
PAOD location 0.802 0.705 (0.046–10.812)
 Proximal 7 (9.2) 3 (42.9)
 Distal 27 (35.5) 9 (33.3)
 Proximal & distal 42 (55.3) 5 (26.3)
Arterial stenotic/occlusive lesion 0.668 0.802 0.705 (0.046–10812)
 Multiple lesions 61 (80.3) 24 (39.3)
Revascularization 16 (21.1) 4 (25.0) 0.223 0.156 4.415 (0.566–34.431)
Wagner classification 0.001 0.003 97.257 (4.807–1,967.729)
 Wagner grade 0 1 (1.3) 0( 0.0)
 Wagner grade 1 6 (7.9) 0 (0.0)
 Wagner grade 2 0 (0.0) 0 (0.0)
 Wagner grade 3 17 (22.4) 2 (11.8)
 Wagner grade 4 34 (44.7) 9 (26.5)
 Wagner grade 5 18 (23.7) 18 (100.0)

Values are presented as number (%).

DFW, diabetic foot wound; PAOD, peripheral arterial occlusive disease; OR, odds ratio; CI, confidence interval; DM, diabetes mellitus; COPD, chronic obstructive pulmonary disease.

Glomerular filtration rate <30.

Vasc Spec Int 2018;34:109-16 https://doi.org/10.5758/vsi.2018.34.4.109
© 2018 The Korean Society for Vascular Surgery